Metallothionein (MT)

Puna Hua: ʻApa Lapi
CAS NO .: 73767-16-5
ʻAno: ʻO ka pauka keʻokeʻo
Hōʻike: 98%

Launch
1. ʻO ka hoʻopaʻa ʻana i nā radical manuahi
2. Detoxification o nā metala kaumaha
3. Wehe i nā metala kaumaha
4. Anti-radiation
5. E komo i ka hoʻokaʻawale cell
6. Hoʻomalu i nā pūnana aʻalolo
7. Hoʻoponopono i nā ʻili lolo i pōʻino

ʻO ka wehewehe e pili ana i Metallothionein (MT)
He nui nā kuleana o Metallothionein. ʻO Metallothionein kahi protein haʻahaʻa haʻahaʻa haʻahaʻa i waiwai i ka cysteine ​​a me nā metala. Ma muli o ka hui pū ʻana i ka nui o nā ion metala a loaʻa iā ia nā hana physiological kūikawā, ua huki nui ia i ka nānā ʻana ma ke kahua o ka biochemistry. Eia nō naʻe, hoʻohana nui ʻia ka metallothionein i nā maʻi maʻi cardiovascular a me ka cerebrovascular a me nā ʻōpū.
ʻO Metallothionein kahi protein haʻahaʻa haʻahaʻa haʻahaʻa me ka mana paʻa metala a me nā waiwai inducibility kiʻekiʻe. ʻO kahi peptide pōkole waiwai nui o ka cysteine ​​​​me ka pilina kiʻekiʻe no nā metala kaumaha like ʻole. He kinikini haʻahaʻa haʻahaʻa molekala me kahi kiʻekiʻe loa o nā koena cysteineine a me nā metala. ʻO nā metala i hui pū ʻia me ia he cadmium, keleawe a me ka zinc, ka mea nui i loko o nā mea ola like ʻole mai nā microorganism a hiki i ke kanaka, a mālama nui ʻia ko lākou mau hale.
ʻO ka hana physiological koʻikoʻi o ka metallothionein ʻo ia ka mea ʻoi aku ka maikaʻi loa o ka radical free radical scavenger i ʻike ʻia a hiki i kēia manawa, ʻo kona hiki ke hoʻokaʻawale i nā radical manuahi e pili ana i mau tausani mau manawa o ka SOD, a ʻo ka hiki ke hoʻopaʻa i nā radical manuahi ʻole he 100 mau manawa o ka glutathione. 25 mau manawa kiʻekiʻe ma mua o ka ginseng, a he hana antioxidant ikaika.
Ma muli o ke ʻano kemika kūikawā o ka metallothionein, ʻaʻole paʻa nā metala i loko, a he ʻano nucleophilic ka hui mercapto, kahi e maʻalahi ai ka metallothionein e launa pū me kekahi mau mea electrophilic, ʻoi aku kekahi mau radical manuahi.
ʻO ka hana a Metallothionein e hoʻokaʻawale i nā radical manuahi e hana nui ia i ka anti-aging, anti-oxidative stress a me apoptosis. ʻO ka Metallothionein kahi mea hoʻoponopono maikaʻi ʻole o ka apoptosis, a loaʻa iā ia kahi hopena pale i nā cell kino maʻamau i ka wā o ka chemotherapy.
Ma ke ʻano he cytoprotectant endogenous ikaika, he mea nui ka metallothionein i ka pale ʻana i ka ʻōnaehana cardiovascular mai ka hōʻeha, ka mea nui i ka pale ʻana i ka ʻeha ischemia-reperfusion. Ua hōʻoia ka hoʻomaʻamaʻa lāʻau lapaʻau hiki i ka ischemic preconditioning ke hoʻonui i ka ʻike o ka metallothionein i loko o ke kino, a laila e hōʻemi i ka pōʻino i hana ʻia e ka reperfusion. Wahi a nā hoʻokolohua, komo ka metallothionein i ka pale o nā cardiomyocytes i mua o ka ischemia, a hoʻemi i ka pōʻino i hana ʻia e ka hypoxia/reoxygenation o nā cardiomyocytes ma ka pale ʻana i ka hana oxidase.
Hoʻokomo ʻia ʻo Metallothionein i ka ʻokoʻa a me ka hoʻonui ʻana o nā pūnaewele tumo. ʻO ka noiʻi e pili ana i ka pilina ma waena o ka metallothionein a me ka maʻi maʻi e pili ana i ka metallothionein a me ka tumorigenesis, e hōʻemi ana i nā mea ʻawaʻawa a me nā hopena ʻaoʻao o nā lāʻau anticancer, a me ka loaʻa ʻana o ke kūʻē ʻana i ka lāʻau o nā cell tumor. ʻO ka hōʻike hemahema o ka metallothionein kekahi o nā hōʻailona o ka tumorigenesis. No laila, ʻo ka noiʻi hohonu ʻana i ka pilina ma waena o ka metallothionein a me nā ʻōpū e manaʻo ʻia e loaʻa i nā lāʻau lapaʻau no ka mālama ʻana i ka maʻi maʻi.